2022-RA-1401-ESGO Comparison of ADNEXmodel, O-RADSand the combinedIOTA simple rules with simple rules risk assessment and simple rules with ADNEX model in discriminating between benign and malignant adnexalmasses

Introduction/Background To compare the IOTA Assessment of Different NEoplasias in adneXa (ADNEX) model, Ovarian-Adnexal Reporting and Data System (O-RADS) combined Simple Rules (SR) with Risk (SRR) assessment SR ADNEX model preoperative discrimination benign malignant adnexal masses (AM). Methodology We conducted a monocentric retrospective study performed between January-2018 to December-2021 which includes consecutive women AM. Surgery histology represented reference standard. classified AM using O-RADS same cohort patients. When resulted ‘inconclusive’, we SRR model. Sensitivity (SE), specificity (SP) diagnostic accuracy (DA) were determined for each testing modality performance O-RADS, + Results Of 514 women, 400 (77.8%) had ovarian tumor 114 (22.2%) tumor. The malignancy risk threshold was set at >10%. SE, SP DA 92,1% (95%CI, 85,5%-96,3%), 88,3% 84,6%-91,2%) 89,1% (86,1%-91,7%), respectively. 93,0% 86,6%-96,9%), 89,3% 85,8%-92,1%) 90.1% 87,2–92,5%), applied SR, 109 (21.2%) cases inconclusive. 87,7% 80,3%-93,1%), 91,8% 88,6%94,3%) 90,9% 88,0%-93,2%), 90,4% 83,4%-95,1%), 93,3% (95%CI 90,3%-95,5%) 92,6% (90%-94,7%), Conclusion similar SE higher than AM; assessment.